Increased effect w/ anti-arrhythmics eg, amiodarone & propafenone; anabolic steroids; alcohol; NSAIDs especially phenylbutazone & azapropazone; antidepressants eg, amitriptyline; antibacterials especially erythromycin, metronidazole, sulphonamides; antifungals eg, ketoconazole & miconazole; thyroxine, clofibrate, allopurinol, disulfiram, cimetidine, danazol, flutamide, tamoxifen, simvastatin, omeprazole, sulphinpyrazone; cranberry juice or cranberry products (eg, cap or conc). Reduced effect w/ barbiturates, glutethimide, aminoglutethimide, primidone, carbamazepine, OCs, rifampicin, griseofulvin, vit K & sucralfate. Increased or decreased effect w/ phenytoin, corticosteroids, ACTH, cholestyramine. Increased risk of bleeding w/ diflunisal, salicylates, dipyridamole, phenylbutazone.